Methadone Treatment Centers Near Greenville, SC

Why Trust Us

As a top-rated website for addiction treatment, AddictionGroup understands the importance of helping you find a reputable addiction clinic. Addiction is a severe problem, so our team comprehensively analyzed hundreds of methadone clinics to provide the best recommendations.

Here are some criteria that our team considers when researching and evaluating addiction clinics:

  • Licenses and accreditation
  • Specializations
  • Treatment approach
  • Experience in treating opioid addiction
  • Insurance coverage

We also employed advanced AI technology to evaluate 3497 patient reviews to identify the best methadone clinic in Greenville. It helps us narrow our recommendations so you can find the best clinic for your needs.

Top 10 Methadone Treatment Centers Near Greenville, SC

Behavioral Health Group - Spartanburg

239 Access Rd, Spartanburg, SC 29303

3.9 out of 5 (77 reviews)

Overall, the reviews for the BHG Methadone treatment center in Spartanburg are overwhelmingly positive. The staff is highly praised, particularly counselors like Amy T, Natasha, Ruth Combs, Kaelie, and Wendy. Many reviewers credit their counselors for helping them on their recovery journey and providing valuable support. The clinic is described as welcoming, caring, and providing a safe environment for patients. The only negative comment mentioned in one review was regarding the cost of the Suboxone program. However, this did not significantly affect the overall positive sentiment towards the center.


  • The counselors at the Methadone treatment center, such as Amy T, Natasha, Ruth Combs, Kaelie, and others, are highly praised for their support, guidance, and care.
  • The staff at the center is friendly, welcoming, and understanding, creating a safe and positive environment for individuals seeking recovery.
  • The program at BHG has been successful in changing lives and helping individuals achieve their treatment goals.

Phoenix Center

1400 Cleveland St, Greenville, SC 29607

3.3 out of 5 (84 reviews)

This Methadone treatment center has received positive reviews for its diverse counseling options, with one reviewer specifically praising counselor Melissa M. for being non-judgmental and caring. The center is also described as clean and sanitary, with friendly and accommodating staff members. Additionally, the center is praised for its detox program and the help it provides in getting individuals back on track in life.


  • The center offers a variety of classes and counseling options to support individuals on their recovery journey.
  • Melissa M. is highly praised as a down-to-earth, genuine, non-judgmental counselor who provides a comfortable and supportive experience.

Medasic Suboxone Clinic

300 John St Unit 4B, Greer, SC 29651

4.7 out of 5 (27 reviews)

The reviews for this Methadone treatment center are overwhelmingly positive. Many reviewers specifically mention the friendly and caring staff, with Brandi and Nikki being highly praised. The center is commended for its individualized approach to treatment, as well as its acceptance of all insurance types. Overall, the center is described as a lifesaver and highly recommended by those who have been helped.


  • The staff is friendly, caring, and supportive.
  • The doctors are knowledgeable and provide proper medical treatment.
  • The clinic takes all insurance, including Medicaid and Medicare.

Greenville Metro Treatment Center

602 Airport Rd C, Greenville, SC 29607

3 out of 5 (43 reviews)

This Methadone treatment center has received overwhelmingly positive reviews from several satisfied patients. The staff, including the doctors, nurses, counselors, and the director, are highly dedicated to the well-being and success of their patients. The center is known for going above and beyond to meet the treatment needs of the patients and has been instrumental in saving lives and supporting long-term sobriety. Overall, the staff is friendly, caring, and genuinely invested in their patients' recovery. This center comes highly recommended by many satisfied individuals.


  • Dedicated and caring staff members: The staff is highly dedicated to their jobs and the well-being of all patients. They go above and beyond to meet treatment needs and provide support.
  • Supportive atmosphere: Patients feel treated like human beings and real people at this treatment center. The nurses, counselors, and director all create a supportive and non-judgmental environment for recovery.
  • Effective treatment results: Multiple reviews mention that this place has saved lives and helped patients maintain sobriety. The staff understands and supports the recovery process, making this center recommended for anyone seeking treatment for opioid addiction.

Southwest Carolina Treatment Center

341 W Beltline Blvd, Anderson, SC 29625

4.6 out of 5 (82 reviews)

Overall, the reviews for the Methadone treatment center are positive. The staff, including counselors like Ms. Tish, Brittany, Candace, Stephanie, and Sterling, are highly praised for their caring and attentive attitudes. The center is commended for providing effective treatment and creating a welcoming atmosphere. There are mentions of long wait times, but some reviewers have found ways to minimize them. Payment for treatment is mentioned as a downside, but it is seen as a small price to pay for recovery.


  • The staff at the Southwest Carolina Treatment Center are praised for their professionalism, caring attitude, and dedication to helping patients. Multiple counselors are specifically mentioned as being understanding, supportive, and going above and beyond for their patients.
  • The treatment center is described as having a welcoming and friendly atmosphere. They are commended for their low turnover rate and the positive impact it has on the overall experience for patients. The receptionist is also mentioned as being kind and always having a smile on her face.
  • The treatment provided at the center is effective, with patients expressing gratitude for the positive changes in their lives as a result of the treatment. The counselors and staff are commended for their contributions to these life-changing transformations.

Solutions Recovery Center, Inc

520 Lowndes Hill Rd, Greenville, SC 29607

3.8 out of 5 (86 reviews)

The positive reviews for the Methadone treatment center highlight the life-changing experience it provides, with individuals expressing gratitude for the tools and support offered. Reviewers mention the comprehensive knowledge and in-depth teachings of the 12-step program, as well as the sense of community and family-like atmosphere created by the staff. Many reviewers credit the center with saving their lives and helping them overcome addiction.


  • Comprehensive program: Solutions Recovery Center provides a comprehensive approach to opioid addiction treatment, including teaching the 12 steps, providing a deeper understanding of addiction, and offering tools for a better life.
  • Supportive community: Many reviewers highlighted the sense of community and support at Solutions Recovery Center. They felt a strong bond with staff and fellow participants, which helped them in their recovery journey.
  • Life-changing experience: Multiple reviewers mentioned that Solutions Recovery Center had a positive and transformative impact on their lives. They credited the program with helping them get clean, rebuild their lives, and improve their relationships.
  • Note that these pros are based on the information provided in the reviews and may not provide a complete picture of the treatment center. It is always recommended to conduct further research and consider individual needs when choosing a treatment center.

Palmetto Carolina Treatment Center

325 Inglesby Pkwy unit f, Duncan, SC 29334

4.1 out of 5 (37 reviews)

Overall, the reviews for the Methadone treatment center are positive. Many reviewers praise the counselors, particularly Grace Holtzclaw, for their caring and supportive approach to treatment. The center is described as professional, efficient, and effective, with a staff that treats patients with respect and kindness. The center is seen as a life-saving resource for those who are serious about changing their lives and getting back on track.


  • The counselors at this treatment center, especially Grace Holtzclaw, are highly praised for their caring and personal approach to patients' recovery.
  • The staff at this center are described as concerned, caring, and professional, providing efficient and effective service.
  • Patients feel respected and valued at this center, being treated as individuals rather than just addicts.

South Carolina Addiction Treatment Detox & Residential

1187 Holland Rd, Simpsonville, SC 29681

4.7 out of 5 (32 reviews)

The Methadone treatment center has received positive reviews overall. Patients appreciate the friendly and caring staff who are recovering addicts themselves, offering a supportive environment. The facility is commended for its top-of-the-line care, good food, and family-like atmosphere. The center is highly recommended for those seeking help with opioid addiction.


  • Friendly and understanding staff, many of whom are recovered addicts themselves
  • Family environment and supportive atmosphere
  • Top-of-the-line care and effective recovery program


157 Brozzini Ct Suite A-D, Greenville, SC 29615

3.5 out of 5 (23 reviews)

The reviews consistently mention the amazing staff at the Methadone treatment center, with specific praise for Erika, Heather, Karen, and the administrative office staff. The staff is described as caring, helpful, professional, and treating patients like family or friends. The positive experiences mentioned include feeling supported, encouraged, and like their problems and concerns are heard. The center has made improvements, particularly in decreased wait times, and is seen as a place where patients can find success and recovery if they are willing to take responsibility and honestly evaluate their problems.


  • The staff at the Methadone treatment center are described as amazing, caring, and professional. Patients feel supported and encouraged in their recovery journey.
  • The administrative staff is praised for their friendly and efficient service, setting a positive tone for each visit.
  • The new director has made noticeable improvements, such as decreased wait times, and demonstrates experience and competence in running the facility.

Lantana Recovery

301 Augusta St Unit 101, Greenville, SC 29601

5 out of 5 (9 reviews)

Lantana Recovery is a highly recommended Methadone treatment center in Greenville, SC. The facility provides excellent care and has a compassionate and understanding staff who are dedicated to helping residents overcome their addictions. The program offers various services and also includes a family support group to provide holistic support for both the individual and their loved ones.


  • Excellent care and dedicated team: The facility provides excellent care and has a dedicated team that is friendly and committed to helping residents overcome their addictions.
  • Compassionate and understanding staff: The staff at Lantana Recovery is compassionate, understanding, and always ready to answer questions and provide support.
  • Comprehensive program with family support: Lantana Recovery offers a comprehensive program that addresses all facets of recovery, including teaching treatment. They also have a weekly family support group, which can be beneficial for both the individual in treatment and their family members.

What is Methadone?

Methadone is a synthetic opioid agonist for Opioid Use Disorder (OUD). Many people in recovery rely on methadone as part of their treatment program.

However,  methadone can be addictive when misused. You should always take methadone under a healthcare professional’s supervision to prevent unwanted side effects.


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How Does Methadone Work?

Methadone binds with brain receptors activated by other opioids like heroin and morphine. It reduces cravings and withdrawal symptoms.

Opioid-dependent people who take methadone don’t experience the same kind of euphoria. One of methadone’s benefits is its long duration of action, allowing it to have a slow onset and prolonged effect.

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Forms of Methadone

Various forms of methadone are available, depending on your treatment plan. Your doctor can also determine the best methadone form suitable for you.

Here are the common forms of methadone:3 

  • Tablet: Methadone tablets are taken orally. You can swallow it whole or mix it in water if it's a dispersible tablet.
  • Liquid: You can also take methadone as a liquid. This is usually prescribed to those with difficulty swallowing tablets or capsules. The liquid concentrate contains 10 milligrams of methadone per milliliter.
  • Injection: Methadone can also be administered as an injection. It’s an alternative for those who can't take oral medication. 

How Long Does Methadone Treatment Usually Last?

It’s recommended to stay on methadone treatment for at least 12 months.

Some may even be on methadone treatment for 20 years.5 This is because opioid addiction is a chronic condition that requires ongoing to prevent relapse. 

Other factors that affect the duration of methadone treatment include:

  • The severity of the addiction
  • Your response to the treatment
  • Overall health 
  • Specific recovery goals

Once you’ve achieved stability, gradually tapering the methadone dose is essential. It helps minimize any withdrawal symptoms.

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Possible Side Effects and Risks of Methadone

Methadone also comes with possible side effects and risks. These side effects will vary for everyone depending on their body’s reaction to the drug.

According to the Substance Abuse and Mental Health Services Administration (SAMHSA), common side effects of methadone include:1

  • Nausea and vomiting
  • Restlessness
  • Slow breathing
  • Itchy skin
  • Heavy sweating
  • Constipation
  • Sexual problems
  • Mood swings 
  • Mental clouding

These side effects and risks are why gradual tapering of methadone is essential. It allows you to adjust to fewer doses, reducing the risk of severe side effects.


Methadone is a synthetic opioid agonist used for opioid use disorder. It binds with opioid receptors in the brain and helps reduce cravings and withdrawal symptoms. 

Methadone can be addictive and has side effects, so you should only take methadone under a professional's supervision. Gradually tapering off the drug also prevents any severe side effects.


  1. “What is Methadone?” Substance Abuse and Mental Health Services Administration (SAMHSA).
  2. "How do medications to treat opioid use disorder work?" National Institute on Drug Abuse, 2021.
  3. "Understanding the Forms of Methadone.” MedMark Treatment Centers. 
  4. "Methadone." The Centre for Addiction and Mental Health, 2021.
  5. Malervy J. "How long should you be on Methadone?" Recovery Centers of America.
  6. "How much does opioid treatment cost?" National Institute on Drug Abuse, 2021. 

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