Updated on February 25, 2025
4 min read

Updated Drug and Alcohol Statistics for South Carolina

Substance use disorders in South Carolina have undergone significant shifts over the past two decades, impacting individuals, families, and communities in both urban and rural regions. These updated drug and alcohol statistics highlight the changing dynamics of opioid misuse, stimulant resurgence, and alcohol abuse patterns, providing objective insight into the populations most affected.

From the rapid emergence of synthetic opioids to the revival of methamphetamine use and consistently elevated alcohol misuse, the data underscores the complexity of South Carolina’s substance use landscape. The following sections focus on numerical findings that document these trends and shed light on disparities across regions, demographics, and specific drug types.

Key Statistics at a Glance

  • 32.6 per 100,000 drug overdose mortality rate in 2022, surpassing the national rate of 28.6
  • 1,760% increase in fentanyl-related emergency department admissions from 2020 to 2022
  • 82% of opioid-related deaths attributed to fentanyl and its analogs
  • 45% of stimulant overdose deaths in rural areas linked to methamphetamine

These data points demonstrate the severity of South Carolina’s substance use issues and frame each category of drug misuse within the state. Below, statistics on opioids, stimulants, alcohol, demographic disparities, and geographic differences are detailed in dedicated sections.

Opioids and the Fentanyl Surge

Escalating opioid misuse, especially fentanyl, has reshaped the state’s overdose profile.

  • Prescription opioid misuse accounted for 28% of primary drug treatment admissions between 2005 and 2015
  • Self-reported fentanyl use among emergency department patients rose 1,760% from 2020 to 2022
  • Heroin use statewide declined by 16% over the same period
  • Fentanyl and its analogs now contribute to 82% of opioid-related fatalities

These figures illustrate how synthetic opioids have taken center stage in overdose statistics, prompting higher emergency department visits and mortality rates.

Indicator2005–20152020–2022
Prescription Opioids in Treatment Admissions 28% (avg.) 18% (avg.)
Fentanyl ED Admissions (Rate of Increase) Base Level +1,760%
Heroin Use Rate (Change) Gradual Rise -16%

The data shows a consistent transition away from heroin toward potent synthetic opioids, underscoring fentanyl’s growing influence on South Carolina’s overdose trends.

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Stimulant Use Trends

Methamphetamine and cocaine continue to affect both urban and rural communities, with varying degrees of severity.

  • Methamphetamine-related treatment admissions tripled between 2015 and 2022
  • Meth lab seizures in the Upstate region increased by 231% from 2007 to 2009
  • Cocaine-related emergency department visits rose 82% from 2020 to 2022
  • 58% of cocaine-positive toxicology reports also detected fentanyl

Stimulant misuse shows a notable synergy with opioids, particularly in instances of polysubstance use involving fentanyl.

StimulantKey TrendTimeframe
Methamphetamine Admissions up 3× 2015–2022
Meth Lab Seizures (Upstate) +231% 2007–2009
Cocaine ED Visits +82% 2020–2022

While opioids command much national attention, these figures highlight an ongoing stimulant crisis, especially in rural and lower-income communities.

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Alcohol Use Patterns

Alcohol misuse continues to place a substantial burden on public health, despite positive trends among adolescents.

  • Underage drinking (past 30 days) among high school students dropped from 10.4% in 2020 to 9.8% in 2023
  • 10.8% of adults met criteria for alcohol use disorder in 2021, a rate 15% higher than the Southeast average
  • Binge drinking episodes increased by 14% during the COVID-19 pandemic
  • Drunk driving fatalities rose 22% between 2020 and 2022
  • Youth-focused interventions may be contributing to decreased underage consumption, yet adult alcohol misuse persists at alarming levels.

    CategoryStatistic
    Underage Drinking (High School) 9.8% (Past 30 Days)
    Adult AUD Rate 10.8%
    Binge Drinking (COVID-19 Period) +14%
    Drunk Driving Fatalities (2020–2022) +22%
    Chronic Liver Disease Mortality Share 18% of Alcohol-Related Deaths

    Adult alcohol abuse remains a leading cause of fatalities and long-term health issues, especially in counties with fewer treatment facilities.

    Demographic Disparities

    Substance use patterns vary significantly by race, age, and gender, highlighting inconsistencies in treatment and outcomes.

    • Non-Hispanic Black residents face 2.1× higher rates of cocaine-related arrests compared to White residents
    • White individuals comprise 82% of fentanyl fatalities
    • Access to medications for opioid use disorder is 4.4× higher for White patients
    • Males account for 69% of methamphetamine and 73% of heroin treatment admissions

    Racial variations in overdose mortality and treatment reflect longstanding inequities, with younger adults (18–25) also showing notably high polysubstance use rates.

    DemographicKey Statistic
    Black Residents (Cocaine Arrests) 2.1× Higher than White Residents
    White Residents (Fentanyl Fatalities) 82% of Deaths
    MOUD Access 4.4× Higher for White Patients
    Male (Meth/Heroin Admissions) 69% / 73% of Admissions

    Bridging these disparities can involve examining where prevention and treatment resources are most lacking and adjusting access accordingly.

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    Urban-Rural Differences

    Geographic location influences access to care, overdose rates, and the specific substances most commonly misused.

    • Synthetic opioid death rates are 28% higher in urban areas (18.3 vs. 14.3 per 100,000)
    • Rural counties reported 167% (Lancaster) and 110% (Orangeburg) increases in overdose mortality between 2018–2019
    • Pee Dee region overdose rate stands at 41.2 per 100,000, nearly double the Lowcountry’s 20.6
    • Rural clinics face 57% longer wait times for SUD treatment than urban centers

    Such data demonstrates the pronounced differences in healthcare infrastructure and overdose prevalence based on population density.

    RegionOverdose Rate (per 100K)Key Fact
    Pee Dee 41.2 High Meth Influence
    Lowcountry 20.6 Lower Overdose Rate
    Urban Counties 18.3 28% Higher Synthetic Opioid Fatalities
    Rural Counties 14.3 Fewer MOUD Providers

    The urban-rural divide extends to infrastructure, with fewer treatment resources available in many rural parts of the state.

    Key Statistics Summary

    • Statewide opioid mortality at 32.6 per 100,000 ranks higher than in 42 other states
    • Illicit drug use rate stands at 12.43%, slightly lower than the 13.01% national average
    • Rural overdose spikes in certain counties exceed 100% increases over a single year
    • Adult alcohol use disorder prevalence remains 15% above the regional benchmark

    From rising methamphetamine admissions to striking fentanyl-related statistics, South Carolina’s substance use patterns underscore the continued need for data-based awareness. The numbers also highlight how social and demographic factors shape patterns of addiction, pointing to significant challenges in addressing each substance category.

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Updated on February 25, 2025
15 sources cited
Updated on February 25, 2025
  1. CDC Data Brief 440. National Center for Health Statistics, 2023.
  2. CDC Data Brief 491. National Center for Health Statistics, 2023.
  3. Drug Abuse and Addiction Statistics. Cornerstone Healing Center, 2022.
  4. Racial Disparities in South Carolina. Council on Criminal Justice, 2022.
  5. DAODAS Stats and Reports. Department of Alcohol and Other Drug Abuse Services, 2024.
  6. 2020 SC County-Level Profiles on Substance Use Related Indicators. DAODAS, 2020.
  7. Behavioral Health Progress Report. South Carolina Behavioral Health Coalition, 2021.
  8. NDIC Meth Overview. U.S. Department of Justice, 2009.
  9. Rehab.com Study. Newswire, 2023.
  10. State Profile - South Carolina. Office of National Drug Control Policy, 2016.
  11. PMC 10953696. National Library of Medicine, 2022.
  12. PubMed 39612232. National Library of Medicine, 2024.
  13. South Carolina BH Barometer Volume 6. SAMHSA, 2021.
  14. 2021 NSDUH South Carolina. SAMHSA, 2022.
  15. SCStatehouse Gov AAR2023. South Carolina Legislature, 2023.

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