Most drugs affect the brain’s reward system, causing euphoria and flooding the brain with the neurotransmitter dopamine. Increased dopamine levels cause the reinforcement of pleasurable but unhealthy behaviors like taking drugs, which leads people to continue the behavior.
As a person uses drugs, the brain adapts by reducing the ability of cells in the reward center to respond to it. When this change occurs, a person feels less high than the high they felt when first taking the drug—an effect known as tolerance.
An increased tolerance might make someone take more of the drug to achieve the same high and cause them to become less and less able to derive pleasure from other things they once enjoyed. An increased tolerance will also make someone experience unpleasant withdrawal symptoms when they don’t take the drug. At this point, people often use drugs or alcohol to keep from feeling bad rather than for their pleasurable effects.
Repeated use of drugs can also damage the essential decision-making center of the brain, known as the prefrontal cortex. When the frontal cortex isn’t working correctly, people can’t decide to stop taking the drug—even when faced with severe consequences.
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Some of the most addictive drugs in the world include:
Opioids are a class of drugs made from the opium poppy plant. These addictive substances are potent painkillers that block pain signals between the brain and the body. Other medical uses for opioids include anesthesia, suppression of diarrhea, replacement therapy for opioid use disorder, reversing opioid overdose, and suppressing coughs.
Codeine is a pain reliever used to treat mild to moderately severe pain. Codeine is also used to reduce coughing. Codeine is available as a single-ingredient product, combined with acetaminophen or aspirin, and in some cough and cold medications.
Hydrocodone is a semi-synthetic opioid that acts as an analgesic (pain reliever) and an antitussive (cough suppressant). Hydrocodone can also produce feelings of euphoria and is a prevalent drug of abuse.
Oxycodone is a semi-synthetic opioid drug prescribed for pain as Tylox®, Percodan®, and OxyContin®. This drug creates feelings of relaxation and euphoria and is often abused. Street Names for oxycodone include Hillbilly Heroin, Kicker, OC, Ox, Roxy, Perc, Oxy.
Meperidine hydrochloride, often prescribed as Demerol, is a drug used to treat moderate to severe pain.
Fentanyl is a synthetic opioid that treats severe pain, typically advanced cancer pain. Fentanyl is 50 to 100 times more potent than morphine. Fentanyl is often sold through illegal drug markets for its heroin-like effect.
Methadone is a medication approved by the Food and Drug Administration (FDA) to treat opioid use disorder (OUD). Methadone is a long-acting full opioid agonist and a schedule II controlled medication.
When taken as prescribed, methadone is safe and effective. Methadone helps individuals achieve and sustain recovery and to reclaim active and meaningful lives.
Common side effects of opioid use include:
Dangers of opioid use include:
An average of 128 Americans die every day from an opioid overdose.
Heroin is a type of opioid drug made from morphine. Heroin appears as a white or brown powder, or a black sticky substance known as black tar heroin. Heroin users inject, sniff, snort, or smoke heroin. Some street names for heroin are horse, smack, and hell dust.
Side effects of heroin use include:
The dangers of heroin use include developing any of the following health consequences:
Cocaine is a stimulant drug made from the coca plant. Cocaine looks like a fine, white powder, or a crystallized rock. Popular nicknames for cocaine include Coke, Blow, Crack, Rock, and Snow.
Dangers of cocaine use include:
Ethyl alcohol, or ethanol, is an ingredient found in wine, beer, and liquor. Alcohol belongs to a class of drugs called depressants that slow the functioning of the body’s systems.
The side effects of alcohol use include:
Alcohol abuse increases the risk of developing several health consequences, including:
Nicotine is a powerful stimulant drug that speeds up the messages traveling between the brain and body. It is the primary psychoactive ingredient in tobacco products.
The following side effects may occur when using tobacco products that contain nicotine:
When a large amount of nicotine is taken, users may experience the following dangerous effects:
Stimulants are a type of drug that speed up the body’s systems.
Adderall is a prescription drug that is used to treat attention-deficit hyperactivity disorder (ADHD). Adderall is also used illicitly as a study aid, to stay awake, and to suppress appetites.
Concerta is another prescription drug that’s used to treat attention deficit hyperactivity disorder (ADHD).
Ritalin is a prescription medicine used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy.
Ecstasy is the street name for 3,4-methylenedioxymethamphetamine (MDMA). It is chemically similar to stimulants and hallucinogens, producing feelings of increased energy, pleasure, emotional warmth, and distorted sensory and time perception.
People who use Ecstasy usually take it as a capsule or tablet, though some swallow it in liquid form or snort the powder.
Methamphetamine is a stimulant that speeds up the body's systems. It is prescribed medically to treat obesity and ADHD as Desoxyn.
Meth is also used as a recreational drug and is smoked, snorted, or injected. Street names for meth include Speed, Ice, Shards, Bikers Coffee, Stove Top, Tweak, Yaba, Trash, Chalk, Crystal, Crank, Shabu.
Dexedrine sulfate is a long- or short-acting capsule, taken orally, that is primarily used to treat attention deficit hyperactivity disorder (ADHD). Dexedrine is also used to treat narcolepsy.
Common side effects of stimulant use include:
The dangers of taking high doses of stimulants include:
Barbiturates are a type of drug used to depress the central nervous system (CNS). Barbiturates are generally only used to treat severe and extreme cases of insomnia, but they can also be used to control seizures and as an adjunct to anesthesia.
Xanax is used to treat anxiety, panic disorder, and anxiety associated with depression.
Valium is used to treat anxiety, muscle spasm, alcohol withdrawal, and sedatives before surgery or to treat seizures.
Klonopin is used to treat the symptoms of seizures and panic disorder.
Ativan is used to treat the symptoms of anxiety disorders.
Librium is used to treat the symptoms of anxiety.
“Sleeping pills” is a term that refers to prescription or over-the-counter medicines that help users fall or stay asleep. Sleeping pills belong to a type of drugs called hypnotics, and can have serious side effects if abused.
Phenazepam is a benzodiazepine drug that is used to treat some types of mental illness. Some of the concerning side effects of phenazepam include loss of coordination, drowsiness, and amnesia.
Common side effects of barbiturates include:
Serious side effects of barbiturates include:
Symptoms of substance use disorder (SUD) include one or more of the following symptoms within 12 months:
Drug addiction treatment options include inpatient, outpatient, partial hospitalization, or detox programs. Drug addiction therapies can consist of medications, behavioral therapies, or their combination. The right treatment program depends on the patient’s individual needs and on the types of drugs they use.
You don’t have to overcome your addiction alone. Professional guidance and support is available. Begin a life of recovery by reaching out to a specialist today.
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