Kratom Uses, Risks & Addiction Treatment

Kratom is a stimulant medication that has a risk for physical dependence, addiction, and dangerous side effects. Addiction symptoms vary from person to person, depending on individual factors and the use of other drugs.
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Kratom is a plant used to boost mood, increase physical endurance, ease anxiety, and treat pain. Kratom has a long history of traditional medicinal use in Africa and Southeast Asia, but its recreational use in the U.S. is steadily increasing.

Although not currently listed as a controlled substance, kratom misuse is associated with physical dependence, addiction, and dangerous side effects. Kratom is not approved by the U.S. Food and Drug Administration (FDA) for any medical use, and the Drug Enforcement Administration (DEA) lists kratom as a Drug of Concern. Drugs of Concern are substances that, while not currently banned by the Controlled Substances Act, pose risks to individuals who abuse them.

Understanding kratom's use, physical and psychological effects, and health risks are essential for preventing severe side effects and addiction.

An estimated 3 to 5 million people in the United States use kratom, and the number of kratom-related calls to U.S. poison centers increased 10-fold from 2010 to 2015.

What is Kratom?

Kratom, known scientifically as Mitragyna speciose, is a tree native to several tropical Southeast Asian countries, including Thailand, Malaysia, Indonesia, and Papua New Guinea. Several alternative names for kratom exist, including:

  • Thom
  • Thang
  • Biak
  • Ketum
  • Kakuam
  • Ithang

Kratom leaves contain compounds with mind-altering and stimulant effects, and kratom products have long been used in Africa and Southeast Asia to manage medical conditions. Kratom leaves are commonly crushed and brewed into tea, chewed, or smoked. The leaves are also ingested in capsule, tablet, or extract form to produce the desired physical or psychological effects.

Kratom is commonly sold on the internet as an extract, gum, or powder in packets with warnings against human consumption. Although kratom is not currently an illegal substance in the U.S., several states and cities have enacted bans on the sale or use of kratom.

As a recreational drug, kratom uses include elevating mood, increasing physical endurance, and improving sexual performance. As a medicinal drug, kratom leaves are used to treat several conditions, including:

  • Anxiety
  • Depression
  • Cough
  • Diabetes
  • Diarrhea
  • High blood pressure
  • Pain
  • Opiate withdrawal

According to the FDA, individuals should avoid kratom use for treating medical conditions or as an alternative to prescription opioids.

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How Does Kratom Impact the Brain?

Recreationally, individuals use kratom to get high. The kratom dosage impacts the drug’s effects. Consumption of low kratom doses produces stimulant effects and consumption of high doses produces sedative effects. Kratom leaves contain two main psychoactive components: mitragynine and 7-hydroxymitragynine. These compounds bind to opioid receptors in the brain, producing sedative effects such as:

  • Pleasurable feelings
  • Sedation
  • Decreased pain
  • Increased calmness
  • Drowsiness

Mitragynine also binds to other receptors in the brain to generate kratom’s stimulant effects, including increased:

  • Energy
  • Alertness
  • Sociability
  • Talkativeness
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Risks of Kratom

Kratom use is associated with several health risks, including severe physical and psychological side effects. Reported kratom side effects include:

  • Nausea
  • Itching
  • Sweating
  • Dry mouth
  • Increased urination
  • Suppressed appetite
  • Abnormal heart rhythm
  • Vomiting
  • Drowsiness
  • Constipation
  • Weight loss
  • Insomnia
  • Kidney toxicity
  • Seizures

In some users, kratom use can also cause severe psychotic symptoms, including:

  • Hallucinations
  • Delusions
  • Confusion

Due to reports about the dangers of kratom use, the FDA continues to warn consumers not to use any products labeled as containing kratom or its mind-altering compounds, mitragynine, and 7-hydroxymitragynine. More research is needed to determine kratom's safety and long-term side effects.

Despite its dangers, there is an increase in kratom street use in Western countries as a natural alternative for self-treatment of opioid withdrawal and pain.

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Kratom Addiction

By binding to receptors in the brain, kratom alters the levels of chemicals involved in the body’s reward pathways, motivating individuals to continue using the drug. Over time, kratom misuse can lead to physical dependence and addiction. Individuals who use high levels of kratom over an extended period are at a higher risk of addiction.

Kratom Addiction Symptoms

Kratom addiction symptoms vary from person to person, depending on individual factors and the use of other drugs. An individual addicted to kratom may show several signs, including:

  • Feeling an intense need to use kratom regularly
  • Gradually needing to take higher kratom doses to achieve the same physical effects
  • Experiencing an inability to focus on routine daily tasks
  • Being unable to stop using kratom
  • Experiencing financial difficulties connected to kratom use
  • Resorting to dangerous behaviors to obtain kratom, such as stealing
  • Engaging in risky behaviors while under the influence of kratom
  • Experiencing withdrawal symptoms when stopping or limiting kratom use
  • Loss of interest in usual activities
  • Changes in eating or sleeping patterns
  • Isolation from loved ones
  • Poor hygiene
Graphic of woman going through withdrawal.

Kratom Withdrawal

Like other drugs with opioid-like effects, kratom can cause physical dependence. Physical dependence occurs when the body adapts to functioning with the drug present. When an individual develops a kratom dependence and subsequently stops using the drug, unpleasant withdrawal symptoms occur.

Kratom withdrawal symptoms include:

  • Muscle aches
  • Sleeping difficulties
  • Irritability
  • Anger
  • Aggression
  • Behavioral changes
  • Runny nose
  • Jerky movements
Icon of pill with warning sign

Kratom Overdose

Although limited information exists regarding overdose rates, kratom is linked to multiple death reports. However, most of these individuals also ingested other substances, so it is challenging to determine kratom’s role in the deaths. In addition, kratom is sometimes contaminated or laced with other potentially deadly substances. Mixing kratom with other drugs or alcohol is dangerous and should be avoided.

A 2019 study found 11 kratom-associated deaths between 2011 and 2017. Of these 11 deaths, nine involved the use of other drugs, such as antihistamines, alcohol, cocaine, and fentanyl. In 2017, the FDA reported at least 44 deaths related to kratom, with at least one case linked to pure kratom.

If a kratom overdose is suspected, seek emergency medical attention, or call 911 immediately. Find a local poison control center by calling the Poison Help hotline: 1-800-222-1222.

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Kratom Addiction Treatment

Currently, there are no specific medical treatments for kratom addiction. Additional research on kratom addiction treatment is needed to determine which methods are effective. However, several treatment approaches may be helpful, including:

Kratom’s mind-altering effects may make it challenging to quit using the drug without assistance. Find professional treatment options today.

Ready to Make a Change?


“Kratom.” DEA,

NIDA. "Kratom." National Institute on Drug Abuse, 8 Apr. 2019, Accessed 26 Feb. 2020.

Commissioner, Office of the. “FDA and Kratom.” U.S. Food and Drug Administration, FDA,

Fluyau, Dimy, and Neelambika Revadigar. “Biochemical Benefits, Diagnosis, and Clinical Risks Evaluation of Kratom.” Frontiers in psychiatry vol. 8 62. 24 Apr. 2017,

Veltri, Charles, and Oliver Grundmann. “Current perspectives on the impact of Kratom use.” Substance abuse and rehabilitation vol. 10 23-31. 1 Jul. 2019,

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Updated on: June 24, 2020
Addiction Group Staff
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Medically Reviewed: March 12, 2020
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Annamarie Coy,
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