Fentanyl, also known as lonsys, subsys, and duragesic, is a pain relieving narcotic. Fentanyl is 50 to 100 times stronger than morphine.
Prescription drugs similar to fentanyl include oxycodone, codeine, and hydrocodone.
Fentanyl is a schedule 2 prescription drug with several serious side effects. Here are the most common:
An increase in fentanyl popularity is thought to be a driving force of the opioid epidemic. Almost 30% of opioid prescriptions are abused. Fentanyl abuse is heavily linked to future heroin abuse. 80% of people that abuse fentanyl go on to build heroin dependency.
Fentanyl is highly addictive and highly potent. This combination increases the risk of a fentanyl overdose. In some parts of the United States, fentanyl overdoses increased 500% in one year. Fentanyl overdoses are often treated with naloxone, which reverses the opioid’s effects.
Fentanyl, despite its illicit drug use, also has medicinal properties. Transdermal patches of fentanyl are often prescribed to treat isolated severe pain (i.e., back pain, knee pain, etc.). A fentanyl patch is often abused for the fentanyl within the patch. Once extracted, the fentanyl may be taken orally, nasally, or intravenously.
Fentanyl can also be created in illegal labs. The fentanyl created in illegal labs differs greatly from medical fentanyl. Fentanyl created for illegal drug use is often mixed or “cut” with synthetic opioids. The additional substances, unmonitored fentanyl potency, and excessive use of street-grade fentanyl contribute to countless overdoses and dependencies. Street-grade fentanyl can also have varying responses to naloxone, due to the addition of other substances.
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The amount of time fentanyl stays in your system varies based on several individualized factors. Factors include body fat, age, gender, diet, genetics, and more.
This drug test detects fentanyl in urine within 24 hours of the last use. Fentanyl remains detectable in the body for up to 72 hours from last use.
Fentanyl drug use can’t be consistently detected by drug testing. Fentanyl, even when taken orally, goes through extensive bodily filtering. This process leaves behind undetectable traces of Fentanyl and its metabolites.
Blood drug tests detect fentanyl for up to 72 hours from last use.
Hair drug tests are often used to establish a brief history of fentanyl use. Fentanyl isn’t detectable in hair for the first few days after the last use. However, once fentanyl is in the hair, it can be detected for up to 3 months. Hair drug tests are often used in tandem with positive urine or blood tests to reveal a pattern of substance abuse.
Drug screenings are designed to detect fentanyl and its metabolites norfentanyl and desropionylfentanyl. Repeated fentanyl drug abuse increases the level of these metabolites. This increase makes positive fentanyl drug tests more likely.
The half-life of fentanyl varies with each route of administration. Intravenous (IV) fentanyl has a half-life of approx 8 hours. This is the most common route of fentanyl when administered in a hospital setting.
When taken orally, fentanyl has a half-life of approx 20 hours. Although rarer, fentanyl may be administered orally for some surgeries. The time differences for the half-lives are due to the bioavailability of the drug. Bioavailability is defined by how much of a compound (substances, food, medicine, etc.) can be effectively absorbed by the body. IV fentanyl has a much higher level of bioavailability than other routes of administration. This also means the body absorbs the substance quicker. Conversely, oral administration of fentanyl has much lower bioavailability.
This means it takes longer for the body to absorb the fentanyl and, to a degree, limits how much fentanyl is in the body at one time. Simply put, only a small amount of fentanyl remains in saliva. Because of this, saliva drug tests are ineffective at detecting fentanyl.
The amount of time a fentanyl high lasts varies based on individual health factors and by route of administration.
Long-term fentanyl use has its own side effects and dangers. These long-term dangers are prevalent among individuals with drug abuse issues. However, the long term effects are also found in individuals prescribed fentanyl for chronic pain.
Medical professionals will weigh the long-term dangers of fentanyl use against the level and consistency of the pain it's prescribed to treat.
Long-term fentanyl effects include:
These are just a few of the potential hazards of long-term fentanyl use.
The first step to overcoming fentanyl addiction is admitting there’s an issue. Anyone can become addicted to fentanyl. Treatment for fentanyl abuse is the best way to avoid future opioid overdoses.
Treatment programs provide the support and medical oversight needed to beat addiction.
Treatment programs offer two primary forms of treatment:
Don’t fight fentanyl addiction alone. Seek help and remember that it takes time to overcome substance use dependency.
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Baldini, Angee, et al. “A Review of Potential Adverse Effects of Long-Term Opioid Therapy: A Practitioner's Guide.” The Primary Care Companion for CNS Disorders, Physicians Postgraduate Press, Inc., 2012, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466038/
Lee, Jaewon, et al. “Clinical Usefulness of Long-Term Application of Fentanyl Matrix in Chronic Non-Cancer Pain: Improvement of Pain and Physical and Emotional Functions.” Clinics in Orthopedic Surgery, The Korean Orthopaedic Association, Dec. 2016, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114261/
Peng, Philip W. H., and Alan N. Sandler. “A Review of the Use of Fentanyl Analgesia in the Management of Acute Pain in Adults .” Anesthesiology, American Society of Anesthesiologists, 1 Feb. 1999, https://pubs.asahq.org/anesthesiology/article/90/2/576/37742/A-Review-of-the-Use-of-Fentanyl-Analgesia-in-the
Schifano, Fabrizio, et al. “Assessing the 2004-2018 Fentanyl Misusing Issues Reported to an International Range of Adverse Reporting Systems.” Frontiers in Pharmacology, Frontiers Media S.A., 1 Feb. 2019, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367955/
Schwartz, J G, et al. “Measurements of Fentanyl and Sufentanil in Blood and Urine after Surgical Application. Implication in Detection of Abuse.” National Library of Medicine, 1994, https://pubmed.ncbi.nlm.nih.gov/7825555/
Silverstein , Jeffrey, et al. “An Analysis of the Duration of Fentanyl and Its Metabolites ... : Anesthesia & Analgesia.” LWW, 1993, https://journals.lww.com/anesthesia-analgesia/Abstract/1993/03000/An_Analysis_of_the_Duration_of_Fentanyl_and_Its.30.aspx